HLCL-61

Catalog No.: A15870

PRMT5 Inhibitor

HLCL-61

HLCL-61 Chemical Structure

CAS NO. 1158279-20-9

HLCL-61 hydrochloride is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $80.00

Special Price $64.00

10 mg

Regular Price: $100.00

Special Price $80.00

25 mg

Regular Price: $165.00

Special Price $132.00

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Biological Activity

HLCL-61 hydrochloride is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia.
Targets
PRMT5
In vitro DMSO 65 mg/mL (170.64 mM)
Water Insoluble
Ethanol 65 mg/mL (170.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.25 mL 131.26 mL 262.53 mL
0.5 mM 5.25 mL 26.25 mL 52.51 mL
1 mM 2.63 mL 13.13 mL 26.25 mL
5 mM 0.53 mL 2.63 mL 5.25 mL

*The above data is based on the productmolecular weight 380.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15870
Actions Inhibitor
CAS No. 1158279-20-9
Formula C23H24N2O.HCl
M. Wt 380.91
Purity >98%
Synonyms HLCL-61 hydrochloride
SMILES COC1=CC=CC=C1CNCC2=CC3=C(C=C2)N(CC)C4=C3C=CC=C4.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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