HMRG

Catalog No.: A45172
Hydroxymethyl Rhodamine Green Fluorescent Scaffold
HMRG, a hydroxymethyl rhodamine green fluorescent scaffold, exhibits an open non-cyclic structure that enables it to undergo significant dynamic fluorescence changes via a single enzymatic reaction at physiological pH. This characteristic makes HMRG ideal for the development of a range of fluorescent probes. Applications include fluorescence-based detection of diseases such as tumors and diabetic nephropathy, offering valuable tools for biomedical research and diagnostics.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHMRG, a hydroxymethyl rhodamine green fluorescent scaffold, exhibits an open non-cyclic structure that enables it to undergo significant dynamic fluorescence changes via a single enzymatic reaction at physiological pH. This characteristic makes HMRG ideal for the development of a range of fluorescent probes. Applications include fluorescence-based detection of diseases such as tumors and diabetic nephropathy, offering valuable tools for biomedical research and diagnostics.
Product Information
Catalog NumA45172
FormulaC20H16N2O2
Molecular Weight316.35
CAS Number1629965-68-9
SMILESN=C1C=CC2=C(C3=C(CO)C=CC=C3)C4=C(C=C(C=C4)N)OC2=C1
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