Fig. 1 · Structure
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Homoeriodictyol
Metabolite of Eriocitrin
Homoeriodictyol is a flavanone metabolite of Eriocitrin that exhibits a range of biological activities. It enhances synaptic-related protein expression via NCOA4-mediated ferritin autophagy and offers potential cognitive benefits by improving memory impairment in mice through inhibition of the NLRP3 inflammasome. Additionally, Homoeriodictyol protects human endothelial cells against oxidative stress by activating the Nrf2 pathway and preventing mitochondrial dysfunction. Its anticancer properties are demonstrated through the inhibition of survival and migration in androgen-resistant prostate cancer cells, as well as its ability to induce apoptosis and enhance reactive oxygen species activity. Moreover, Homoeriodictyol displays antinociceptive effects in vivo.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 446-71-9 |
| Applications | Metabolite of Eriocitrin |
| Formula | C16H14O6 |
| Molecular Weight | 302.28 |
| SMILES | O=C1C[C@@H](C2=CC=C(O)C(OC)=C2)OC3=CC(O)=CC(O)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.