Fig. 1 · Structure
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HOOCCH2O-PEG4-CH2COOH
PROTAC Linkers
HOOCCH2O-PEG4-CH2COOH is a symmetric polyethylene glycol (PEG) linker designed for use in PROTAC (Proteolysis Targeting Chimera) applications. This compound facilitates the synthesis of Homo-PROTACs, enabling targeted protein degradation in cellular systems. Its unique structure enhances solubility and biocompatibility, making it a valuable tool in drug development and biochemical research focused on modulating protein levels.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 77855-75-5 |
| Applications | PROTAC Linkers |
| Formula | C12H22O9 |
| Molecular Weight | 310.30 |
| SMILES | O=C(O)COCCOCCOCCOCCOCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.