Catalog No.: A16349
hedgehog inhibitor
HPI-4 is a hedgehog (Hh) signaling pathway inhibitor with median inhibitory concentration (IC50) less than 10 μM.
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HPI-4 5mg
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HPI-4 10mg
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HPI-4 50mg
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Biological Activity
Discription HPI-4 is a hedgehog (Hh) signaling pathway inhibitor with median inhibitory concentration (IC50) less than 10 μM.
Product Information
Catalog Num A16349
Formula C17H9Cl2N3O2
Molecular Weight 358.18
CAS Number 302803-72-1
SMILES C1=CC=C2C(=C1)C(=O)NC(=C(C#N)C(=O)C3=C(C=C(C=C3)Cl)Cl)N2
Synonyms Ciliobrevin A

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 65 mg/mL (181.47 mM)
Water Insoluble
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.92 mL 139.59 mL 279.19 mL
0.5 mM 5.58 mL 27.92 mL 55.84 mL
1 mM 2.79 mL 13.96 mL 27.92 mL
5 mM 0.56 mL 2.79 mL 5.58 mL
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