HPK1 antagonist-1

Catalog No.: A65760
HPK1 Antagonist
HPK1 antagonist-1 (I-792) is a selective antagonist of HPK1, a key regulator involved in immune signaling pathways. This compound exhibits significant biological activity by inhibiting HPK1-mediated signaling, making it a valuable tool for investigating its role in cancer progression and immune disorders. Researchers can utilize HPK1 antagonist-1 to explore therapeutic strategies targeting HPK1 in various disease models.
Grouped product items
Size Price Stock Qty
25mg
$1,530.00
In stock
50mg
$1,950.00
In stock
100mg
$2,480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHPK1 antagonist-1 (I-792) is a selective antagonist of HPK1, a key regulator involved in immune signaling pathways. This compound exhibits significant biological activity by inhibiting HPK1-mediated signaling, making it a valuable tool for investigating its role in cancer progression and immune disorders. Researchers can utilize HPK1 antagonist-1 to explore therapeutic strategies targeting HPK1 in various disease models.
Product Information
Catalog NumA65760
FormulaC28H29FN6O2
Molecular Weight500.57
CAS Number2628489-56-3
SMILESO=C1NCC2=C(C3=CN=C4C=C(C=CN43)F)C=CC(NC5=CC=C(C6CCOCC6)C(CN(C)C)=N5)=C12
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