HPK1-IN-16

Catalog No.: A65751
HPK1 Inhibitor
HPK1-IN-16 is a selective inhibitor of hematopoietic progenitor kinase 1 (HPK1), a member of the MAP kinase kinase kinase kinase (MAP4K) family. By specifically targeting HPK1, this compound demonstrates potential in the study of various diseases linked to HPK1 activity, including cancer. HPK1-IN-16 is valuable for research applications focused on the modulation of HPK1-related pathways to better understand disease mechanisms and explore therapeutic interventions.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHPK1-IN-16 is a selective inhibitor of hematopoietic progenitor kinase 1 (HPK1), a member of the MAP kinase kinase kinase kinase (MAP4K) family. By specifically targeting HPK1, this compound demonstrates potential in the study of various diseases linked to HPK1 activity, including cancer. HPK1-IN-16 is valuable for research applications focused on the modulation of HPK1-related pathways to better understand disease mechanisms and explore therapeutic interventions.
Product Information
Catalog NumA65751
FormulaC28H27FN4O
Molecular Weight454.54
CAS Number2294965-95-8
SMILESN#CC1=C(C2=C(C=C(CNC)C=C2C)F)C=C3C(C4=CC=C(C5CCOCC5)C=C4)=NNC3=C1
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