HPK1-IN-49

Catalog No.: A65772
HPK1 Inhibitor
HPK1-IN-49 is a selective inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 value exceeding 100 nM. This compound is utilized in research to study the role of HPK1 in various cellular processes, including immune responses and signal transduction pathways. Its inhibition can provide insights into therapeutic strategies targeting HPK1-related diseases.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHPK1-IN-49 is a selective inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 value exceeding 100 nM. This compound is utilized in research to study the role of HPK1 in various cellular processes, including immune responses and signal transduction pathways. Its inhibition can provide insights into therapeutic strategies targeting HPK1-related diseases.
Product Information
Catalog NumA65772
FormulaC28H29FN6O2
Molecular Weight500.57
CAS Number2845144-97-8
SMILESO=C(NC1)C2=C1C(C3=CN=C4C=C(F)C=CN43)=CN=C2NC5=CC=C(N6CCC[C@H](C(C)(C)O)C6)C=C5
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