HPK1-IN-60

Catalog No.: A65786
HPK1 Inhibitor
HPK1-IN-60 is an inhibitor of the HPK1 protein kinase, which plays a critical role in regulating T cell activation. This compound exhibits significant potential in antitumor immunotherapy research by modulating immune responses. It is a valuable tool for studying the mechanisms of immune regulation and exploring therapeutic strategies in cancer treatment.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHPK1-IN-60 is an inhibitor of the HPK1 protein kinase, which plays a critical role in regulating T cell activation. This compound exhibits significant potential in antitumor immunotherapy research by modulating immune responses. It is a valuable tool for studying the mechanisms of immune regulation and exploring therapeutic strategies in cancer treatment.
Product Information
Catalog NumA65786
FormulaC21H26N8O
Molecular Weight406.48
CAS Number2421199-24-6
SMILESO=C1N(C2=NC(C3=NN=CN3CCC)=CC=C2)CC4=C1C=C(N(C)C)N=C4CNC
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