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HR1

Catalog No.: A49319
Antimicrobial Peptide
HR1 is an antimicrobial peptide that functions as a mastoid protease, increasing the permeability of human erythrocyte membranes. It effectively induces cytoplasmic membrane permeation in both bacteria and mast cells, making it a valuable reagent for studies in microbial resistance and immune response research. Applications of HR1 include investigations into membrane disruption mechanisms and the development of novel antimicrobial therapies.
HR1 80533-94-4 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHR1 is an antimicrobial peptide that functions as a mastoid protease, increasing the permeability of human erythrocyte membranes. It effectively induces cytoplasmic membrane permeation in both bacteria and mast cells, making it a valuable reagent for studies in microbial resistance and immune response research. Applications of HR1 include investigations into membrane disruption mechanisms and the development of novel antimicrobial therapies.
Product Information
Catalog NumA49319
FormulaC71H133N19O15
Molecular Weight1492.93
CAS Number80533-94-4
SequenceIle-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Val-Lys-Lys-Val-Leu-NH2
Sequence shorteningINLKAIAALVKKVL-NH2
SMILES[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)C(C)C)=O)CCCCN)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(N)=O)=O)CC(C)C)=O)CCCCN)=O)C)=O)[C@H](CC)C)=O)C)=O)C)=O)CC(C)C)=O)C(C)C)=O)CCCCN
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