Fig. 1 · Structure
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HS-PEG5-CH2CH2NH2 hydrochloride
PROTAC Linker
HS-PEG5-CH2CH2NH2 hydrochloride is a PROTAC linker designed to facilitate the degradation of target proteins via the proteasome pathway. As part of the polyethylene glycol (PEG) class, this compound provides favorable solubility and biocompatibility, making it an ideal choice for synthesizing PROTAC molecules. Its application supports studies in targeted protein degradation and therapeutic development in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1446256-16-1 |
| Applications | PROTAC Linker |
| Formula | C12H28ClNO5S |
| Molecular Weight | 333.87 |
| Synonyms | Thiol-PEG5-amine hydrochloride |
| SMILES | SCCOCCOCCOCCOCCOCCN.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.