Fig. 1 · Structure
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hUP1-IN-1 potassium
hUP1 Inhibitor
hUP1-IN-1 potassium is a specific inhibitor of the hUP1 enzyme, exhibiting Ki and Kis Urd values of 375 nM and 635 nM, respectively. This compound demonstrates significant inhibitory activity against hUP1-catalyzed reactions, achieving approximately 70% inhibition at a concentration of 1 μM. hUP1-IN-1 potassium is a valuable reagent for research focused on cancer mechanisms and potential therapeutic interventions related to hUP1.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 118803-30-8 |
| Applications | hUP1 Inhibitor |
| Formula | C7H5KN2O2 |
| Molecular Weight | 188.23 |
| SMILES | N#CC1=C(C)C=C(O[K])NC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.