Fig. 1 · Structure

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hUP1-IN-1

hUP1 Inhibitor

hUP1-IN-1 is a selective inhibitor of the human Ubiquitin-specific Protease 1 (hUP1), exhibiting Ki and Kis values of 375 nM and 635 nM, respectively. This compound demonstrates a significant inhibitory effect, achieving 70% inhibition of hUP1-catalyzed reactions at a concentration of 1 μM. hUP1-IN-1 is particularly valuable for research focusing on oncogenic pathways, making it a relevant tool for investigating cancer-related mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 5444-02-0
Applications hUP1 Inhibitor
Formula C7H6N2O2
Molecular Weight 150.13
SMILES
CC1=CC(O)=NC(O)=C1C#N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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