Fig. 1 · Structure

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Hydrangenol 8-O-glucoside

AChE Inhibitor

Hydrangenol 8-O-glucoside is an acetylcholinesterase (AChE) inhibitor, demonstrating an IC50 value of 22.66 μM. Isolated from Hydrangea macrophyllus, this compound exhibits significant activity in inhibiting the PCA (passive cutaneous anaphylaxis) reaction. Its properties make it a useful tool for research on neurodegenerative diseases and allergic responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 67600-94-6
Applications AChE Inhibitor
Formula C21H22O9
Molecular Weight 418.39
Synonyms Hydrangenol 8-O-β-D-glucopyranoside
SMILES
O=C1C(C(CC(C2=CC=C(O)C=C2)O1)=CC=C3)=C3O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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