Hydrocortisone hemisuccinate hydrate

Catalog No.: A35948
Anti-inflammatory Agent
Hydrocortisone hemisuccinate hydrate serves as an orally active glucocorticoid anti-inflammatory agent, primarily targeting and inhibiting pro-inflammatory cytokines such as IL-6 and IL-3 with IC50 values of 6.7 μM and 21.4 μM, respectively. This compound exhibits significant anti-inflammatory and immunomodulatory activities, making it valuable in research applications related to ulcerative colitis and recurrent oral ulcers. Its ability to modulate inflammation positions it as a key reagent for studies in inflammatory disease pathways.
Grouped product items
Size Price Stock Qty
25mg
$65.00
In stock
50mg
$100.00
In stock
100mg
$155.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHydrocortisone hemisuccinate hydrate serves as an orally active glucocorticoid anti-inflammatory agent, primarily targeting and inhibiting pro-inflammatory cytokines such as IL-6 and IL-3 with IC50 values of 6.7 μM and 21.4 μM, respectively. This compound exhibits significant anti-inflammatory and immunomodulatory activities, making it valuable in research applications related to ulcerative colitis and recurrent oral ulcers. Its ability to modulate inflammation positions it as a key reagent for studies in inflammatory disease pathways.
Product Information
Catalog NumA35948
FormulaC25H36O9
Molecular Weight480.55
CAS Number83784-20-7
SMILESC[C@@]12[C@](CC[C@]2(O)C(COC(CCC(O)=O)=O)=O)([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])[C@H](C1)O.O
SynonymsHydrocortisone 21-hemisuccinate hydrate
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2