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Hydroxy-Amino-bis(PEG1-C2-Boc)

PROTAC Linker

Hydroxy-Amino-bis(PEG1-C2-Boc) is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an alkyl/ether structure that enhances solubility and stability in biological systems. It plays a crucial role in facilitating targeted protein degradation, making it valuable for research applications in drug discovery and cellular biology. Its unique properties enable effective coupling of target proteins to E3 ligases, advancing the development of innovative therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1415800-34-8
Applications	PROTAC Linker
Formula	C₂₀H₃₉NO₇
Molecular Weight	405.53
SMILES	CC(C)(C)OC(CCOCCN(CCO)CCOCCC(OC(C)(C)C)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.