Hydroxy-PEG10-acid is a PEG-based non-cleavable linker designed for the synthesis of Antibody-Drug Conjugates (ADCs). Its primary mechanism involves the formation of stable covalent bonds facilitating the attachment of cytotoxic agents to antibodies. This linker enhances the therapeutic efficacy of ADCs by improving solubility and distribution while minimizing systemic toxicity. It finds application in drug development aimed at targeted cancer therapies and other diseases requiring precise delivery systems.
Hydroxy-PEG10-acid is a PEG-based non-cleavable linker designed for the synthesis of Antibody-Drug Conjugates (ADCs). Its primary mechanism involves the formation of stable covalent bonds facilitating the attachment of cytotoxic agents to antibodies. This linker enhances the therapeutic efficacy of ADCs by improving solubility and distribution while minimizing systemic toxicity. It finds application in drug development aimed at targeted cancer therapies and other diseases requiring precise delivery systems.
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