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Hydroxy-PEG3-ethyl acetate

PROTAC Linker

Hydroxy-PEG3-ethyl acetate is a polyethylene glycol (PEG)-based linker designed for Protein Degradation Targeting Chimeras (PROTACs) synthesis. This compound facilitates the conjugation of target proteins with E3 ligases, promoting ubiquitination and subsequent proteasomal degradation. It serves as an essential tool in the development of innovative therapeutic strategies in drug discovery and cancer research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	118988-04-8
Applications	PROTAC Linker
Formula	C₁₀H₂₀O₆
Molecular Weight	236.26
SMILES	O=C(OCC)COCCOCCOCCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.