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Hydroxy-PEG3-PFP ester

PROTAC Linker

Hydroxy-PEG3-PFP ester is a polyethylene glycol (PEG)-based PROTAC linker that facilitates the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances solubility and biocompatibility, making it a valuable tool in the development of targeted protein degradation methodologies. Hydroxy-PEG3-PFP ester is particularly useful for research applications involving targeted therapy and the modulation of protein levels within cellular systems.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1807537-40-1
Applications	PROTAC Linker
Formula	C₁₅H₁₇F₅O₆
Molecular Weight	388.28
Synonyms	Pentafluorophenyl 3-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}propanoate
SMILES	O=C(CCOCCOCCOCCO)OC1=C(C(F)=C(C(F)=C1F)F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.