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Hydroxy-PEG8-CH2-Boc

PROTAC Linkers

Hydroxy-PEG8-CH2-Boc is a polyethylene glycol (PEG)-based linker designed for PROTAC (proteolysis-targeting chimera) applications. This compound facilitates the selective degradation of target proteins through the ubiquitin-proteasome pathway. Its extended PEG structure enhances solubility and biocompatibility, making it suitable for the synthesis of various PROTACs in chemical biology research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2869101-36-8
Applications	PROTAC Linkers
Formula	C₂₂H₄₄O₁₁
Molecular Weight	484.58
Synonyms	HO-PEG8-CH2COOtBu
SMILES	O=C(COCCOCCOCCOCCOCCOCCOCCOCCO)OC(C)(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.