Fig. 1 · Structure
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Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da)
Cosolvent
Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) functions primarily as a cosolvent, enhancing the solubility of low-solubility compounds in solid dispersion systems (SDDs). This polymer demonstrates a favorable safety profile, exhibiting no acute, subchronic, or chronic toxicity in rat models, with an oral LD50 greater than 2.5 g/kg. It is widely utilized in pharmaceutical formulations to improve bioavailability and stability of drug compounds.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 71138-97-1 |
| Applications | Cosolvent |
| Molecular Weight | 20-100 (kDa) |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.