Fig. 1 · Structure
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HZ52
Cat. No.
A76451
CAS
1077626-51-7
5-lipoxygenase inhibitor
HZ52 is a reversible inhibitor of 5-lipoxygenase, effectively blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes. This compound is valuable for research applications aimed at understanding inflammatory responses and the role of leukotrienes in various diseases. HZ52 may be useful in exploring therapeutic strategies for conditions such as asthma, arthritis, and other inflammatory disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1077626-51-7 |
| Applications | 5-lipoxygenase inhibitor |
| Formula | C24H26ClN3O2S |
| Molecular Weight | 456.00 |
| SMILES | ClC1=CC(NC2=CC=C(C=C2)C3=CC=CC=C3)=NC(SC(C(O)=O)CCCCCC)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.