i-AZD1775 TFA

Catalog No.: A57260
Anticancer Agent
i-AZD1775 TFA is an immobilizable analogue of AZD1775, functioning as a selective inhibitor of the WEE1 kinase. This compound exhibits significant potential in inhibiting cell cycle regulation, enabling the investigation of its efficacy in cancer cell lines. i-AZD1775 TFA is valuable for studies focused on anticancer therapies, particularly in exploring combination treatments and resistance mechanisms in various tumor types.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptioni-AZD1775 TFA is an immobilizable analogue of AZD1775, functioning as a selective inhibitor of the WEE1 kinase. This compound exhibits significant potential in inhibiting cell cycle regulation, enabling the investigation of its efficacy in cancer cell lines. i-AZD1775 TFA is valuable for studies focused on anticancer therapies, particularly in exploring combination treatments and resistance mechanisms in various tumor types.
Product Information
Catalog NumA57260
FormulaC31H38F3N9O4
Molecular Weight657.69
CAS Number2858813-30-4
SMILESO=C(C(F)(F)F)O.O=C1C2=CN=C(NC3=CC=C(N4CCN(CCCN)CC4)C=C3)N=C2N(N1CC=C)C5=CC=CC(C(C)(C)O)=N5
Useful Calculator

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