I-BOP

Catalog No.: A63189
TP Agonist
I-BOP is a potent thromboxane A2 receptor (TP) agonist with a binding affinity (KD) of 0.61 nM. It facilitates cellular proliferation by activating the PI3K signaling pathway in vascular smooth muscle cells. Additionally, I-BOP exhibits a biphasic, dose-dependent modulation of excitatory postsynaptic potentials in hippocampal neurons, making it a valuable tool for research in vascular biology and neurophysiology.
Grouped product items
Size Price Stock Qty
100µg
$175.00
In stock
500µg
$710.00
In stock
1mg
$1,160.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionI-BOP is a potent thromboxane A2 receptor (TP) agonist with a binding affinity (KD) of 0.61 nM. It facilitates cellular proliferation by activating the PI3K signaling pathway in vascular smooth muscle cells. Additionally, I-BOP exhibits a biphasic, dose-dependent modulation of excitatory postsynaptic potentials in hippocampal neurons, making it a valuable tool for research in vascular biology and neurophysiology.
Product Information
Catalog NumA63189
FormulaC23H29IO5
Molecular Weight512.38
CAS Number128719-90-4
SMILESO=C(O)CCC/C=C\C[C@H]1[C@](O2)([H])CC[C@]2([H])[C@@H]1/C=C/[C@@H](O)COC3=CC=C(I)C=C3
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