Fig. 1 · Structure
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Ibuprofen acyl-β-D-glucuronide
Cat. No.
A68886
CAS
115075-59-7
TRPA1 Antagonis
Ibuprofen acyl-β-D-glucuronide is a selective antagonist of the TRPA1 ion channel. This compound effectively reduces the calcium response induced by allyl isothiocyanate (AITC), exhibiting an IC50 value of 60 μM. It is a valuable tool for investigating TRPA1-related pathways and for exploring potential therapeutic applications in pain modulation and sensory signal transduction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 115075-59-7 |
| Applications | TRPA1 Antagonis |
| Formula | C19H26O8 |
| Molecular Weight | 382.40 |
| Synonyms | Ibuprofen glucuronide |
| SMILES | CC(C(O[C@@H]1O[C@H](C(O)=O)[C@H]([C@@H]([C@H]1O)O)O)=O)C2=CC=C(C=C2)CC(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.