Fig. 1 · Structure
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ICeD-2
Cell Death Inducer
ICeD-2 is a potent inducer of cell death that specifically targets HIV-1 infected cells by exploiting HIV-1 protease activity. This compound effectively inhibits the hydrolysis of Gly-Pro-AMC by dipeptidyl peptidase DPP8 and DPP9, leading to enhanced degradation of infected cells. Additionally, ICeD-2 demonstrates strong stabilization of DPP9 in peripheral blood mononuclear cells (PBMCs), making it a valuable tool for research in HIV-related studies and cell death mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 3050598-72-3 |
| Applications | Cell Death Inducer |
| Formula | C20H29N3O |
| Molecular Weight | 327.46 |
| SMILES | O=C(N1CC(C=CC=C2)=C2C1)[C@@H](N)[C@@H](CC3)CC[C@H]3N4CCCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.