Fig. 1 · Structure
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ICI 192605
TXA2R Antagonist
ICI 192605 is a potent antagonist of the thromboxane A2 receptor (TXA2R), a key regulator in cell signaling pathways involving prostaglandins. This compound effectively inhibits the contraction of isolated guinea pig trachea triggered by U-46619, demonstrating its potential in respiratory research. ICI 192605 is valuable for studies investigating the role of TXA2R in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 117621-64-4 |
| Applications | TXA2R Antagonist |
| Formula | C22H23ClO5 |
| Molecular Weight | 402.87 |
| SMILES | OC(CC/C=C\C[C@@H]1[C@H](C(C=CC=C2)=C2O)O[C@H](C(C=CC=C3)=C3Cl)OC1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.