Fig. 1 · Structure

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ICI 198615

Cat. No. A76474 CAS 104448-53-5

Lipoxygenase Inhibitor

ICI 198615 is a potent inhibitor of lipoxygenase, targeting the enzymes involved in the metabolism of eicosanoids. By inhibiting lipoxygenase activity, ICI 198615 effectively attenuates the early phase of bronchoconstriction induced by endothelin-1 (ET-1). This compound is useful for research focused on respiratory disorders and inflammatory responses related to eicosanoid signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 104448-53-5
Applications Lipoxygenase Inhibitor
Formula C28H28N4O6S
Molecular Weight 548.61
SMILES
O=C(OC1CCCC1)NC2=CC3=C(C=C2)C=NN3CC4=CC=C(C(NS(=O)(C5=CC=CC=C5)=O)=O)C=C4OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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