ICI 216140

Name: ICI 216140
Brand: Adooq Bioscience
SKU: A59101
Rating: 5 (288 reviews)

Catalog No.: A59101

GRP/Bombesin Receptor 2 Antagonist

ICI 216140 is a potent GRP/bombesin receptor 2 antagonist with an IC50 value of 2 nM. This compound effectively inhibits Bombesin-stimulated pancreatic amylase secretion and mitigates Bombesin-induced increases in blood pressure. ICI 216140 is valuable for research into the physiological roles of bombesin receptors and their implications in various pathophysiological conditions.

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ICI 216140 124001-41-8 GRP/Bombesin Receptor 2 Antagonist

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Grouped product items
Size	Price	Stock
500µg	$120.00	In stock
1mg	$240.00	In stock
5mg	$625.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	ICI 216140 is a potent GRP/bombesin receptor 2 antagonist with an IC50 value of 2 nM. This compound effectively inhibits Bombesin-stimulated pancreatic amylase secretion and mitigates Bombesin-induced increases in blood pressure. ICI 216140 is valuable for research into the physiological roles of bombesin receptors and their implications in various pathophysiological conditions.

Product Information

Catalog Num	A59101
Formula	C45H65N13O8
Molecular Weight	916.08
CAS Number	124001-41-8
Sequence	{N-Isobutyryl}-His-Trp-Ala-Val-{d-(Ala)}-His-Leu-NHMe
Sequence shortening	{N-Isobutyryl}-HWAV-{d-(Ala)}-HL-NHMe
SMILES	C([C@H](NC([C@H](CC1=CN=CN1)NC(C(C)C)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(NC)=O)CC(C)C)=O)=O)C)=O)[C@H](C)C)=O)C)=O)C=3C=4C(NC3)=CC=CC4

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