Fig. 1 · Structure
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ICI 56780
Antimalarial Agent
ICI 56780 is an antimalarial agent that targets the schizont stages of Plasmodium species, exhibiting significant blood schizonticidal activity in rodent malaria models. Additionally, ICI 56780 demonstrates the ability to develop parasite resistance in P. berghei-infected mice, highlighting its potential implications in understanding resistance mechanisms. This compound is valuable for research focusing on malaria pathology, treatment strategies, and the development of novel antimalarial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 28130-28-1 |
| Applications | Antimalarial Agent |
| Formula | C23H25NO5 |
| Molecular Weight | 395.45 |
| SMILES | O=C(C1=CNC2=CC(OCCOC3=CC=CC=C3)=C(CCCC)C=C2C1=O)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.