Fig. 1 · Structure
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Icopezil
AchE Inhibitor
Icopezil is a selective inhibitor of acetylcholinesterase (AchE), a key enzyme involved in the hydrolysis of acetylcholine. Its ability to enhance cholinergic transmission makes it a valuable compound for research in Alzheimer's disease and other cognitive disorders. By increasing acetylcholine levels in the synaptic cleft, Icopezil offers potential insights into therapeutic strategies targeting cholinergic deficits in neurodegenerative conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 145508-78-7 |
| Applications | AchE Inhibitor |
| Formula | C23H25N3O2 |
| Molecular Weight | 375.46 |
| Synonyms | CP-118,954 |
| SMILES | O=C1NC2=CC3=C(C=C2C1)C(CCC4CCN(CC4)CC5=CC=CC=C5)=NO3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.