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Icrocaptide

P-selectin Inhibitor

Icrocaptide (ITF1697) is a selective P-selectin inhibitor that disrupts the Ca2+-dependent fusion of Weibel-Palade bodies with the plasma membrane. This peptide is effective in the early phases of endothelial activation, leading to the inhibition of both P-selectin and von Willebrand factor secretion. Icrocaptide is suitable for research exploring various microvascular disorders and their underlying mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	169543-49-1
Applications	P-selectin Inhibitor
Formula	C₂₁H₄₀N₈O₅
Molecular Weight	484.59
Synonyms	ITF1697
SMILES	C([C@@H](N(C(CN)=O)CC)CCCCN)(=O)N1[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.