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iCRT 14

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CRT inhibitor

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Catalog No. A16218

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
iCRT 14 5mg A16218-5

Regular Price: $60.00

Special Price: $54.00

iCRT 14 10mg A16218-10

Regular Price: $100.00

Special Price: $90.00

iCRT 14 50mg A16218-50

Regular Price: $450.00

Special Price: $405.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

iCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).

iCRT 14

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Chemical Information

Catalog Num A16218
Actions Inhibitor
M. Wt 375.44
Formula C21H17N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 677331-12-3
Synonyms iCRT14, iCRT-14
SMILES CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)N(C(=O)S3)C4=CC=CC=C4

Biological Activity

Description
iCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.64 mL 133.18 mL 266.35mL
0.5 mM 5.33 mL 26.64 mL 53.27 mL
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL

*The above data is based on the productmolecular weight 375.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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