iCRT 14

Catalog No.: A16218

CRT inhibitor

iCRT 14

iCRT 14 Chemical Structure

CAS NO. 677331-12-3

iCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$450.00
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Biological Activity

iCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).
In vitro DMSO 35 mg/mL (93.22 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.64 mL 133.18 mL 266.35 mL
0.5 mM 5.33 mL 26.64 mL 53.27 mL
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL

*The above data is based on the productmolecular weight 375.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16218
Actions Inhibitor
CAS No. 677331-12-3
Formula C21H17N3O2S
M. Wt 375.44
Solubility DMSO
Purity >98%
Synonyms iCRT14, iCRT-14
SMILES CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)N(C(=O)S3)C4=CC=CC=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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