Biological Activity
iCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.64 mL | 133.18 mL | 266.35 mL |
0.5 mM | 5.33 mL | 26.64 mL | 53.27 mL |
1 mM | 2.66 mL | 13.32 mL | 26.64 mL |
5 mM | 0.53 mL | 2.66 mL | 5.33 mL |
*The above data is based on the productmolecular weight 375.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16218 |
---|---|
Actions | Inhibitor |
M. Wt | 375.44 |
Formula | C21H17N3O2S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 677331-12-3 |
Synonyms | iCRT14, iCRT-14 |
SMILES | CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)N(C(=O)S3)C4=CC=CC=C4 |
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