iCRT3

Catalog No.: A16847

Wnt/β-catenin antagonist

iCRT3

iCRT3 Chemical Structure

CAS NO. 901751-47-1

iCRT3 is an antagonist of Wnt/β-catenin signaling with an IC50 of 8.2 nM in the Wnt responsive STF16-luc reporter assays.

Availability: In stock

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5 mg

Regular Price: $80.00

Special Price $64.00

10 mg

Regular Price: $120.00

Special Price $96.00

50 mg

Regular Price: $480.00

Special Price $384.00

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Biological Activity

iCRT3 is an antagonist of Wnt/β-catenin signaling with an IC50 of 8.2 nM in the Wnt responsive STF16-luc reporter assays.
In vitro DMSO 69 mg/mL (174.89 mM)
Water Insoluble
Ethanol 69 mg/mL (174.89 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.73 mL 253.47 mL
0.5 mM 5.07 mL 25.35 mL 50.69 mL
1 mM 2.53 mL 12.67 mL 25.35 mL
5 mM 0.51 mL 2.53 mL 5.07 mL

*The above data is based on the productmolecular weight 394.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16847
Actions Antagonist
CAS No. 901751-47-1
Formula C23H26N2O2S
M. Wt 394.53
Purity >98%
Synonyms iCRT 3, iCRT-3
SMILES O=C(NCCC1=CC=CC=C1)CSCC2=C(C)OC(C3=CC=C(CC)C=C3)=N2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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