Fig. 1 · Structure
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IDD388
ALR2 Inhibitor
IDD388 is a selective inhibitor of aldose reductase (ALR2), exhibiting an IC50 value of 30 nM. This compound demonstrates a high degree of selectivity for ALR2 over aldose reductase type 1 (ALR1), with an IC50 of 14 μM. IDD388 is widely utilized in research focused on diabetic complications and associated metabolic disorders, making it a valuable tool for studying the role of ALR2 in these processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 314297-26-2 |
| Applications | ALR2 Inhibitor |
| Formula | C16H12BrClFNO4 |
| Molecular Weight | 416.63 |
| SMILES | O=C(COC1=CC(Cl)=CC=C1C(NCC2=CC=C(C=C2F)Br)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.