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IDN-7314

Caspase Inhibitor

IDN-7314 is a potent pan-Caspase inhibitor that exhibits an IC50 range of 0.2-7 nM for all tested Caspases. This compound significantly inhibits Jo2-induced caspase-3/7 activity and reduces the procoagulant effect of tissue factor in hepatocytes. IDN-7314 is valuable for investigating mechanisms related to chemically induced hepatitis, fulminant liver failure, and apoptotic liver injury.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	254750-11-3
Applications	Caspase Inhibitor
Formula	C₂₂H₁₇F₆N₃O₇
Molecular Weight	549.38
SMILES	O(CC([C@@H](NC([C@@H](NC(C(NC1=C(F)C=CC=C1F)=O)=O)C)=O)CC(O)=O)=O)C2=C(F)C(F)=CC(F)=C2F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.