Fig. 1 · Structure
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Idoxuridine hydrate
Antiviral Agent
Idoxuridine hydrate is an iodinated analogue of thymidine that primarily targets viral DNA polymerase, acting as a potent antiviral agent. It demonstrates substantial inhibitory effects on viral replication, particularly in the context of herpes simplex keratitis and other viral eye infections. In studies involving feline herpesvirus, Idoxuridine exhibits an IC50 value of 4.3 μM, underscoring its potential utility in antiviral research and therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 17140-71-5 |
| Applications | Antiviral Agent |
| Formula | C9H13IN2O6 |
| Molecular Weight | 372.11 |
| Synonyms | 5-Iodo-2′-deoxyuridine hydrate; 5-IUdR hydrate; IdUrd hydrate |
| SMILES | OC[C@@H]1[C@H](C[C@H](N2C(NC(C(I)=C2)=O)=O)O1)O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.