IITZ-01

Catalog No.: A20192

Lysosomotropic autophagy inhibitor

IITZ-01

IITZ-01 Chemical Structure

CAS NO. 1807988-47-1

IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.

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5 mg
$100.00
10 mg
$180.00
50 mg
$580.00
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Biological Activity

IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.72 mL 103.62 mL 207.25 mL
0.5 mM 4.14 mL 20.72 mL 41.45 mL
1 mM 2.07 mL 10.36 mL 20.72 mL
5 mM 0.41 mL 2.07 mL 4.14 mL

*The above data is based on the productmolecular weight 482.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20192
Actions Inhibitor
M. Wt 482.51
Formula C26H23FN8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1807988-47-1
Synonyms IITZ 01; IITZ01; Autophagy inhibitor IITZ-01
SMILES FC1=CC=C(NC2=NC(N3CCOCC3)=NC(NC4=CC=C(C5=NC6=CC=CC=C6N5)C=C4)=N2)C=C1

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