IITZ-01

Catalog No.: A20192

Lysosomotropic autophagy inhibitor

IITZ-01

IITZ-01 Chemical Structure

CAS NO. 1807988-47-1

IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$180.00
50 mg
$580.00
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Biological Activity

IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.
In vitro DMSO 89 mg/mL (184.44 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.72 mL 103.62 mL 207.25 mL
0.5 mM 4.14 mL 20.72 mL 41.45 mL
1 mM 2.07 mL 10.36 mL 20.72 mL
5 mM 0.41 mL 2.07 mL 4.14 mL

*The above data is based on the productmolecular weight 482.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20192
Actions Inhibitor
CAS No. 1807988-47-1
Formula C26H23FN8O
M. Wt 482.51
Solubility DMSO
Purity >98%
Synonyms IITZ 01; IITZ01; Autophagy inhibitor IITZ-01
SMILES FC1=CC=C(NC2=NC(N3CCOCC3)=NC(NC4=CC=C(C5=NC6=CC=CC=C6N5)C=C4)=N2)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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