Target & Activity
| Target | Activity | Value |
|---|---|---|
| IKK-β | IC50 | 8.5 nM |
| IKK-α | IC50 | 250 nM |
Fig. 1 · Structure
Documents & Downloads
ACHP Hydrochloride (IKK-2 inhibitor VIII)
Cat. No.
A11452
CAS
406209-26-5
IKK Inhibitor
IKK-2 inhibitor VIII is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 406209-26-5 |
| Applications | IKK Inhibitor |
| Formula | C21H25ClN4O2 |
| Molecular Weight | 400.9 |
| Synonyms | IKK-beta inhibitor; IKK-2 inhibitor VIII |
| SMILES | C1CC1COC2=CC=CC(=O)C2=C3C=C(C(=C(N3)N)C#N)C4CCNCC4.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.