IKK epsilon-IN-1

Catalog No.: A16298

IKK-ε inhibitor

IKK epsilon-IN-1

IKK epsilon-IN-1 Chemical Structure

CAS NO. 1292310-49-6

IKK epsilon-IN-1 is a potent IKKε inhibitor; inhibit the in-situ IKK ε-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.

Availability: In stock

Package Price Qty
5 mg
$320.00
10 mg
$480.00
50 mg
$1,400.00
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Biological Activity

IKK epsilon-IN-1 is a potent IKKε inhibitor; inhibit the in-situ IKK ε-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.
In vitro DMSO 57 mg/mL (124.58 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.86 mL 109.28 mL 218.57 mL
0.5 mM 4.37 mL 21.86 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.86 mL
5 mM 0.44 mL 2.19 mL 4.37 mL

*The above data is based on the productmolecular weight 457.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16298
Actions Inhibitor
CAS No. 1292310-49-6
Formula C26H27N5O3
M. Wt 457.52
Solubility DMSO
Purity >98%
SMILES C1COCCC1OC2=C(C=C(C=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5)C#N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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