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IMA-1

Name: IMA-1
Brand: Adooq Bioscience
SKU: A43925
Availability: OutOfStock

Cat. No. A43925 CAS 2315406-63-2

ALOX12-ACC1 interaction inhibitor

IMA-1 is an inhibitor of the interaction between arachidonic acid 12-lipoxygenase (ALOX12) and acetyl-CoA carboxylase 1 (ACC1). This compound has demonstrated significant efficacy in blocking the progression of diet-induced non-alcoholic steatohepatitis (NASH) in male mice and crab-eating monkeys, while not inducing hyperlipidemia. IMA-1 serves as a valuable tool for investigating the underlying mechanisms and potential treatments for NASH.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2315406-63-2
Applications	ALOX12-ACC1 interaction inhibitor
Formula	C₂₇H₂₇N₃O₁₀S₂
Molecular Weight	617.65
SMILES	O=S(C(C=C1)=CC=C1NCC(C=CC=C2OC)=C2O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O)(NC4=NC5=CC=CC=C5S4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.