IMD 0354

Catalog No.: A12837

IKK Inhibitor

IMD 0354 Chemical Structure

CAS NO. 978-62-1

IMD 0354 is an inhibitor of IκB kinase-β (IKKβ) that blocks NF-κB nuclear translocation.

Availability: In stock

Package Price Qty
10 mg
$80.00
25 mg
$150.00
50 mg
$210.00
100 mg
$350.00
10mM * 1mL in DMSO
$72.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

IMD 0354 is an inhibitor of IκB kinase-β (IKKβ) that blocks NF-κB nuclear translocation.
Targets
IKKβ
In vitro (25°C) DMSO 10 mg/mL (26.06 mM)
Water <1 mg/mL (<1 mM)
Ethanol 77 mg/mL (200.69 mM)
In vivo 0.5% CMC/0.25% Tween 80, pH 4 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.06 mL 130.32 mL 260.64 mL
0.5 mM 5.21 mL 26.06 mL 52.13 mL
1 mM 2.61 mL 13.03 mL 26.06 mL
5 mM 0.52 mL 2.61 mL 5.21 mL

*The above data is based on the productmolecular weight 383.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12837
Actions Inhibitor
M. Wt 383.67
Formula C15H8ClF6NO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 978-62-1
Synonyms IMD-0354, IMD0354
SMILES C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)O

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