IMD 0354

Catalog No.: A12837
IKK Inhibitor
IMD 0354 is an inhibitor of IκB kinase-β (IKKβ) that blocks NF-κB nuclear translocation.
Grouped product items
Product Name Price Stock Qty
IMD 0354 10mg
$80.00
In stock
IMD 0354 25mg
$150.00
In stock
IMD 0354 50mg
$210.00
In stock
IMD 0354 100mg
$350.00
In stock
IMD 0354 10mM * 1mL in DMSO
$72.00
In stock
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Adooq Products cited in reputable paper
Adooq's IMD 0354 has been cited by 1 publications
  • Anton Lennikov, .et al. , Angiogenesis, 2018, 21(2): 267-285 PMID: 29332242
  • Biological Activity
    Discription IMD 0354 is an inhibitor of IκB kinase-β (IKKβ) that blocks NF-κB nuclear translocation.
    Targets
    Target Value
    Product Information
    Catalog Num A12837
    Formula C15H8ClF6NO2
    Molecular Weight 383.67
    CAS Number 978-62-1
    SMILES C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)O
    Synonyms IMD-0354, IMD0354
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 9 mg/mL (23.45 mM)
    Water Insoluble
    Ethanol 72 mg/mL (187.66 mM)
    In vivo 2% DMSO+5% Tween 80+0.5% CMC Na 2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.06 mL 130.32 mL 260.64 mL
    0.5 mM 5.21 mL 26.06 mL 52.13 mL
    1 mM 2.61 mL 13.03 mL 26.06 mL
    5 mM 0.52 mL 2.61 mL 5.21 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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