FAP | Adooq Bioscience

Cat. No.: A62990

CAS No.: 115406-25-2

R-75317

R-75317 is a selective antagonist of platelet-activating factor (PAF). It has demonstrated the ability to prevent the decline in creatinine clearance in a rat model of antibody-induced glomerulonephritis, delay the onset of proteinuria, and ameliorate glomerular hypertrophy, mesangial matrix proliferation, and interstitial fibrosis. This compound may serve as a valuable tool in the investigation of glomerulonephritis and related renal pathologies.

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All 3 sizes

Cat. No.: A64613

CAS No.: 80049-85-0

Suc-Gly-Pro-AMC

Suc-Gly-Pro-AMC is a fluorescent substrate designed specifically for the fibroblast activation protein (FAP). It is capable of reacting with recombinant porcine prolyl oligopeptidase, facilitating the study of FAP and prolyl endopeptidase (PREP) activity. This reagent is particularly valuable in glioma research, providing insights into the enzymatic functions associated with tumor progression and microenvironmental interactions.

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2 mg

$65.00

5 mg

$100.00

All 6 sizes

Cat. No.: A64622

CAS No.: 1426305-25-0

ARI-3144

ARI-3144 is a specific substrate for fibroblast activation protein (FAP), designed for effective detection and quantification. When coupled with the fluorophore 7-Amino-4-methylcoumarin (AMC), this substrate facilitates sensitive analysis of FAP activity in various biological samples. ARI-3144 is valuable in research applications related to cancer biology and tissue remodeling, enabling deeper insights into FAP functions and its role in disease progression.

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5 mg

$335.00

10 mg

$515.00

All 5 sizes