Immunoproteasome inhibitor 1 is a potent reversible inhibitor of the immunoproteasome and the proteasome, targeting the β5c, β1i, and β5i subunits with Kis of 1.18, 0.27, and 1.91 μM, respectively. This compound exhibits significant biological activity in modulating protein degradation pathways, making it a valuable tool for investigating the role of the immunoproteasome in various neoplastic diseases. Its unique mechanism of action facilitates research into targeted therapies and mechanistic studies in oncology.
Immunoproteasome inhibitor 1 is a potent reversible inhibitor of the immunoproteasome and the proteasome, targeting the β5c, β1i, and β5i subunits with Kis of 1.18, 0.27, and 1.91 μM, respectively. This compound exhibits significant biological activity in modulating protein degradation pathways, making it a valuable tool for investigating the role of the immunoproteasome in various neoplastic diseases. Its unique mechanism of action facilitates research into targeted therapies and mechanistic studies in oncology.
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