Fig. 1 · Structure
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IMPDH-IN-2
IMPDH Inhibitor
IMPDH-IN-2 is a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH), with IC50 values of 0.15 μM for IMPDH I and 0.17 μM for IMPDH II. This compound exhibits significant antitumor activity, making it valuable for research applications focused on cancer biology and therapeutic development. Its selective inhibition of IMPDH pathways positions it as a relevant tool in the study of nucleotide metabolism and tumor growth inhibition.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 31858-65-8 |
| Applications | IMPDH Inhibitor |
| Formula | C16H18O6 |
| Molecular Weight | 306.31 |
| SMILES | CC1=C(C(C/C=C(CCC(O)=O)\C)=C(C2=C1COC2=O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.