INCB053914 phosphate

Catalog No.: A21444

Pim inhibitor

INCB053914 phosphate

INCB053914 phosphate Chemical Structure

CAS NO. 2088852-47-3

INCB053914 phosphate is an inhibitor of Pim extracted from patent WO 2017044730 A1, compound 1; has an IC50 of less than 35 nM.

Availability: In stock

Package Price Qty
1 mg
$162.00
5 mg
$486.00
10 mg
$828.00
50 mg
$2,484.00
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Biological Activity

INCB053914 phosphate is an inhibitor of Pim extracted from patent WO 2017044730 A1, compound 1; has an IC50 of less than 35 nM.
In vitro DMSO 48 mg/mL (78.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.35 mL 81.76 mL 163.53 mL
0.5 mM 3.27 mL 16.35 mL 32.71 mL
1 mM 1.64 mL 8.18 mL 16.35 mL
5 mM 0.33 mL 1.64 mL 3.27 mL

*The above data is based on the productmolecular weight 611.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21444
Actions Inhibitor
CAS No. 2088852-47-3
Formula C26H29F3N5O7P
M. Wt 611.51
Solubility DMSO
Purity >98%
Synonyms INCB 053914, INCB-053914
SMILES O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[[email protected]]4O)=C3N5C[[email protected]@H](N)[[email protected]](O)[[email protected]@H](C)C5.OP(O)(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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