INCB3344

Catalog No.: A11465

CCR2 antagonist

INCB3344

INCB3344 Chemical Structure

CAS NO. 1262238-11-8

INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.

Availability: In stock

Package Price Qty
5 mg
$171.00
10 mg
$295.00
50 mg
$874.00
100 mg
$1,748.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.31 mL 86.57 mL 173.13 mL
0.5 mM 3.46 mL 17.31 mL 34.63 mL
1 mM 1.73 mL 8.66 mL 17.31 mL
5 mM 0.35 mL 1.73 mL 3.46 mL

*The above data is based on the productmolecular weight 577.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11465
Actions Antagonist
CAS No. 1262238-11-8
Formula C29H34F3N3O6
M. Wt 577.59
Purity >98%
Synonyms INCB 3344, INCB-3344
SMILES CCO[[email protected]]1CN([[email protected]]2([H])CC[[email protected]@](CC2)(C3=CC4=C(OCO4)C=C3)O)C[[email protected]@H]1NC(CNC(C5=CC(C(F)(F)F)=CC=C5)=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy INCB3344 | INCB3344 Supplier | purchase | cost | manufacturer | order | distributor | buy 1262238-11-8| 1262238-11-8 Supplier | purchase 1262238-11-8 | 1262238-11-8 cost | 1262238-11-8 manufacturer | order 1262238-11-8 | 1262238-11-8 distributor
Rewards