|Discription||Iincyclinide, also known as CMT-3 and COL-3, is a MMP inhibitor and a chemically-modified tetracycline with potential antineoplastic activity. Incyclinide inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent also causes mitochondrial depolarization in tumor cells and induces both cellular apoptosis and tissue necrosis.|
|Synonyms||CMT-3; CMT 3; CMT3; COL3; COL-3; COL 3|
Store lyophilized at -20ºC, keep desiccated.
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2