Fig. 1 · Structure
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Inotilone
Mmp2/9 Inhibitor
Inotilone is a selective inhibitor of matrix metalloproteinases MMP-2 and MMP-9, which are key enzymes involved in the metastatic progression of lung cancer. This compound enhances the activity of antioxidant enzymes, contributing to its anti-metastatic properties. Additionally, Inotilone inhibits IκBα phosphorylation and the nuclear translocation of NFκB p65, influencing various signaling pathways including FAK, PI3K/AKT, MAPKs, and NFκB. Inotilone is suitable for research applications focused on cancer metastasis and treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 906366-79-8 |
| Applications | Mmp2/9 Inhibitor |
| Formula | C12H10O4 |
| Molecular Weight | 218.21 |
| SMILES | O=C1/C(OC(C)=C1)=C/C2=CC=C(O)C(O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.