Fig. 1 · Structure
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INSCoV-614(1B)
Mpro/3CLpro Inhibitor
INSCoV-614(1B) is a potent inhibitor of the Mpro (3CLpro) protease, critical for the transcription and replication processes of SARS-CoV-2. It demonstrates significant inhibitory activity, making it a valuable tool for research into the mechanisms of SARS-CoV-2 infection. This compound may contribute to the development of therapeutic strategies targeting viral proteases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2735704-33-1 |
| Applications | Mpro/3CLpro Inhibitor |
| Formula | C23H21ClF3N5O3 |
| Molecular Weight | 507.89 |
| SMILES | Cl[C@H](F)C(N(C1=CC=C(C2=CC=NO2)C=C1)[C@@H](C3=CN=CN=C3)C(NC4CCC(F)(CC4)F)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.